AirTalkr is a multi-protocol Instant Messenger that connects to MSN, Yahoo, GTalk, AOL and ICQ. AirTalkr also has connects to various Web 2.0 services like Flickr and YouTube.
AirTalkr runs on Adobe AIR, so you will need the runtime to use AirTalkr. On top of chatting with your friends, you can watch and search photos from Flickr and videos from YouTube without leaving your desktop. You can view each of your buddies AirCard, a profiling system in AirTalkr that gathers your buddies profile from the Web.